Heterofile Antistoffer.

Transkript

1 November 2014 Pakningsvedlæg, version 2 Heterofile Antistoffer. Det er vigtigt at du returnerer dine resultater, positive som negative. Herved kan andre få oplysning om robustheden af alle de metoder, som er blevet undersøgt. Kittet indeholder tre prøver, Normal, som ikke er tilsat noget 10 mg/l som er tilsat museantistof, SAM (sheep antimouse), i lav koncentration, og 20 mg/l, som er tilsat museantistof i højere koncentration til det samme serum som Normal. Lav dobbeltbestemmelse af den komponent, hvis analysemetode, som ønskes undersøgt for interferens af heterofile antistoffer på alle tre prøver. Udfyld derfor nedenstående skema så detaljeret og udførligt som muligt, og returner det til DEKS, se adresse og mail i footeren. Komponent Fx som i Labterm eller dens NPU-kode Instrument producent og type Reagens(er) Resultat af 1. bestemmelse af Normal + enhed Resultat af 2. bestemmelse af Normal + enhed Resultat af 1. bestemmelse af 10mg/L + enhed Resultat af 2. bestemmelse af 10mg/L + enhed Resultat af 1. bestemmelse af 20mg/L + enhed Resultat af 2. bestemmelse af 20mg/L + enhed Flere kommentarer: Kommentar Revisionshistorie : Første version kun med gamle resultater fra den nordiske undersøgelse : Anden version. Med ny forside til indberetning af resultater til fortsat udbredelse af undersøgelse for interferens af heterofile antistoffer. DEKS Indgang 8, 1. sal Glostrup Hospital 2600 Glostrup Tlf.: Fax: deks@deks.dk

2 Interferences from heterophilic antibodies 2009 Explanation to the al report The labels of the al report consists of: Component The name of the component measured. I have tried to use an understandable name, but many of these components are new to me, so I have used a consensus name if possible. I presume this will cause no problem for those of you who have submitted results for these components as your result has been given. Producer Name of the company that have manufactured the instrument. Different versions may have been collected in a larger group. Instrument Instrument name and type. Results Number of results for this method. Results Number of al results for this method. M First, for each laboratory for each method the fraction of the mean of Replicate 1 and Replicate 2 for sample +SAM and the mean of Replicate 1 and Replicate 2 for sample Normal has been calculated. M in the report is the mean of all the al fractions for each method. Min Minimum value of fraction for this method. Max Maximum value of fraction for this method. Your result Your result, if you have submitted one, is shown here. If one or both of your results for Normal or +SAM is not al, e.g. <0.1 or low, this is indicated as e.g. <0.1/<0.1 or low/low. If you have made any comments to your result, these are presented just beneath your result. 16/ For EQAnord Pål Rustad NKK Page 1 of 14

3 Numerical report Institution: Fürst Medisinsk Laboratorium,, NO-1051 OSLO Contact: Trude Torsnes, Comments: Component Producer Instrument Results Results A-Casein Phadia Immunocap ACTH Roche cobas Siemens Immulite AFP Abbott Architect Brahms Kryptor Diasorin Liaison Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Centaur Immulite A-glatt muskulatur BMD CARIS 1 0 A-lactoglobulin IgA Phadia Immunocap A-lactaalbumin IgA Immunocap Alcalic Phosphatase Bone (BAP) Metra Unknown: Kitname: Metra BAP kit A-LKM BMD CARIS 1 0 A-mitokondrier CARIS ANA Screen Phadia Tecan Genesis RMP Anti Jo 1 BioRad BioPlex 1 0 Anti-Cardiolipin IgG Phadia Immunocap Anti-Cardiolipin IgM Immunocap anti-chrom BioRad BioPlex 1 0 Anti-HBc-Tot Abbott Architect Bio Merieux Vidas Anti-HBe Abbott Architect Anti-HCV Architect Anti-parietalceller BMD CARIS 1 0 anti-pr3 capture Tecan ELISA reader Magellan anti-ribo P BioRad BioPlex anti-rnp 68 BioPlex 1 0 anti-rnp A BioPlex 1 0 anti-ssa-52 BioPlex 1 0 anti-ssa-60 BioPlex 1 0 anti-ssb BioPlex 1 0 Anti-Tg Siemens Immulite Anti-TPO Abbott Architect Berthold Technol. LUMAT LB Brahms Kryptor Page 2 of 14

4 Anti-TPO Roche cobas Modular E Siemens Centaur Immulite BNP Abbott Architect Borrelia IgGAb gp41 Borrelia IgMAb gp41 Beckman Coulter Access Unicel Siemens Centaur DAKO Cytomation Unknown: Kitname: IDEIA Lyme Neuro-borreliosis Unknown: Kitname: IDEIA Lyme Neuro-borreliosis CA 125 Abbott Architect Beckman Coulter Unicel Brahms Kryptor Diasorin Liaison In house AutoDelfia Roche cobas Modular E Siemens Centaur CA 153 Abbott Architect Beckman Coulter Unicel Diasorin Liaison Roche cobas Modular E Siemens Centaur CA 199 Abbott Architect Unicel Brahms CA Diasorin Liaison Roche cobas Modular E Siemens Centaur Immulite CA 72-4 Roche Modular E Calcitonin Siemens CAMA Carbamazepin Olympus Olympus Siemens Centaur Cardiolopin IgG Phadia Immunocap CCP-ab Immuno Page 3 of 14

5 CCP-ab Phadia Immunocap Unknown: Kitname: CDT % Siemens BN Nefelometri CEA Abbott Architect Unicel Diasorin Liaison In house AutoDelfia Roche cobas Modular E Siemens Centaur Immulite Centromer-ab BioRad BioPlex 1 0 Phadia Immunocap Choriongonadotrophin Siemens Centaur CK-MB Abbott Architect Unicel Ortho Vitros Roche cobas Elecsys Modular E Siemens Centaur Immulite CMVIgG Abbott Architect 1 0 CMVIgM Architect COBA Siemens Immulite Cortisol Abbott Architect Beckman Coulter Unicel Roche cobas Modular E Siemens Centaur C-peptid DiaSorin Liaison Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Centaur Immulite cpsa Centaur Crosslaps Roche Modular E CRP Ortho Vitros Page 4 of 14

6 CRP Roche cobas cobas integra Siemens Advia Cyfra 21-1 Roche Modular E D-dimer Stago Star evolution DHEAS Roche cobas Modular E Siemens RIA Digitoxin Roche Modular E 1 0 Siemens Centaur Digoxin Roche cobas Modular E 1 0 Siemens Centaur dsdna BioRad BioPlex Phadia autocab Immunocap e1 (Cat epitelum) Immunocap E146F2-K57 In house interference assay Victor EBNA Diasorin Liaison Biotest Unknown: Kitname: Biotest AntiEBV EBNA ELISA 1 0 EBV VCA IgG Diasorin Liaison Biotest Unknown: Kitname: Biotest AntiEBV VCA IgG ELISA 1 0 EBV VCA IgM Diasorin Liaison Biotest Unknown: Kitname: Biotest AntiEBV VCA IgM ELISA ECP Phadia Immunocap EliA Celiac IgA Immunocap EliA Celiac IgG Immunocap EliA CENP Immunocap EliA Jo-1 Immunocap EliA La Immunocap EliA RNP Immunocap EliA Ro Immunocap EliA Scl-70 Immunocap Page 5 of 14

7 EliA Sm Phadia Immunocap Enolase DiaSorin Liaison EPO Siemens Immulite Ferritin Abbott Architect Beckman Coulter Access Unicel Ortho Vitros Roche cobas Elecsys Modular E Siemens Centaur Immulite Folate Abbott Architect Beckman Coulter Access Unicel Roche cobas Elecsys Modular E Siemens Centaur Immulite Free beta-hcg Brahms Kryptor 2 0 Free PSA Abbott Architect Beckman Coulter Access Unicel Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Immulite Free T3 Abbott Architect Beckman Coulter Unicel Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite Free T4 Abbott Architect Beckman Coulter Access Unicel Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Page 6 of 14

8 Free T4 Siemens Immulite FSH Abbott Architect Beckman Coulter Access Unicel Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite Ftin Roche cobas Gastrin Siemens Immulite GBM-ab BioRad BioPlex 1 0 Phadia Immunocap Gentamycin Siemens Centaur GH Beckman Coulter Unicel DiaSorin Liaison Perkin Elmer AutoDelfia Siemens Immulite Gliadin IgA Phadia Immunocap Granulocyte macrophagecolony stimulating factor BioRad BioPlex H. p. IgG Siemens HAVAb Centaur HAVAb IgG Abbott Architect S/CO= Sample RLU/Cut-off RLU HAVAb IgM Architect Siemens Centaur HBcAb-IgM Abbott Architect S/CO= Sample RLU/Cut-off RLU HBeAg Architect S/CO= Sample RLU/Cut-off RLU HBsAg Architect Siemens Centaur HBVeAb Abbott Architect hcg Architect Unicel BRAHMs Kryptor 1 0 Ortho Vitros Roche cobas Elecsys Modular E Siemens Centaur Page 7 of 14

9 hcg Siemens Immulite hcg beta fritt BRAHMS Kryptor 1 0 Perkin Elmer AutoDelfia HCVAb Siemens Centaur Helicobacter Pylori IgG Bio Merieux Vidas Her-2 Siemens Centaur Heterophilic ab Orion Unknown: Kitname: Clearview IM 1 0 HIV Abbott Architect OBS! Positive sample H.Pylori HIV Ag/Ab Architect Homocystein Architect S/CO= Sample RLU/Cut-off RLU Siemens Centaur Immulite IGE Beckman Coulter Unicel Phadia autocab Immunocap Roche cobas Modular E Siemens Centaur Immulite IgE mod Birk Phadia autocab IGF-1 Siemens Immulite IGFBP1 Medix Biochemica Unknown: Kitname: IEMA Test IGFBP-3 Siemens Immulite Inhibin A Beckman Coulter Unicel Insulin Unicel Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Centaur Immulite Interferon gamma BioRad BioPlex Interleukin 10 BioPlex Siemens Immulite Interleukin 12 BioRad BioPlex Interleukin 13 BioPlex Interleukin 1beta BioPlex Siemens Immulite Interleukin 2 BioRad BioPlex Interleukin 4 BioPlex Interleukin 5 BioPlex Interleukin 6 BioPlex Biosource Immunoassay kit Page 8 of 14

10 Interleukin 6 Roche cobas Siemens Immulite Interleukin 7 BioRad BioPlex Interleukin 8 BioPlex K57F2-K57 Siemens Immulite In house interference assay Victor K57G-K57 Victor La-ab (SSB) Phadia Immunocap LH Abbott Architect Unicel Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite Litium Olympus Olympus Lp(a) Siemens BN Mb Roche cobas MBL In-house Unknown: Kitname: MPO-ab BioRad BioPlex 1 0 Phadia Immunocap Eurodiagnostica Tecan Genesis RMP Unknown: Kitname: Wieslab Capture MPO- ANCA IU-kit MUC1 In house AutoDelfia Myoglobin Abbott Architect Beckman Coulter Unicel Roche cobas Elecsys Modular E Siemens BN Centaur Immulite NSE Diasorin Liaison In house Gammacounter Roche cobas Elecsys Modular E NT-ProBNP cobas Page 9 of 14

11 NT-ProBNP Roche Elecsys Modular E Oestradiol Abbott Architect Beckman Coulter Unicel Roche cobas Modular E Siemens Centaur Ostase Beckman Coulter Unicel Osteocalsin Roche Elecsys Siemens PAPP-A Brahms Kryptor Perkin Elmer AutoDelfia Parathyrin Roche cobas PCT BRAHMS Kryptor Roche cobas Modular E PEP Siemens PGE Centaur Phenobarbital Olympus Olympus Siemens Centaur Phenytoin Olympus Olympus Roche cobas Modular P PLA Siemens Centaur PR3-ab BioRad BioPlex 1 0 Phadia Immunocap Eurodiagnostica Tecan Genesis RMP Unknown: Kitname: Wieslab Capture PR3-ANCA IU kit ProCalcitonin Roche cobas Modular E Progesterone Abbott Architect Roche cobas Elecsys Modular E Siemens Centaur progrp In house AutoDelfia Prolactin Abbott Architect Beckman Coulter Access Page 10 of 14

12 Prolactin Beckman Coulter Unicel BRAHMS Kryptor Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite Protein-S Stago Star evolution PSA Abbott Architect Beckman Coulter Access Unicel Ortho Vitros Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite PTH Abbott Architect Unicel Roche cobas Elecsys Modular E Siemens Centaur Immulite Renin DiaSorin Liaison CIS bio RIA Ro-ab (SSA) Phadia Immunocap Rubella Abbott Architect Diasorin Liaison Rubella IgM Liaison S-100 Roche cobas Elecsys Modular E Scl-70 BioRad BioPlex 1 0 Phadia Immunocap SHBG Abbott Architect Beckman Coulter Access Unicel Perkin Elmer Wizard Roche cobas Page 11 of 14

13 SHBG Roche Modular E Siemens Immulite sil-2r Immulite Sm-ab BioRad BioPlex 1 0 Phadia Immunocap stfr Roche cobas integra Siemens BN Symphoni Phadia autocab Immunocap Syphilis Abbott Architect T3 Architect Beckman Coulter Unicel Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Centaur Immulite T4 Abbott Architect T84F2-K57 Beckman Coulter Unicel Perkin Elmer AutoDelfia Roche cobas Modular E Siemens Centaur In house interference assay Victor T84F-K57 Victor T84G-K57 Victor T84hF2-K57 Victor T84hF-K57 Victor T84scFv-K57 Victor TATI (tumour-associated trypsin inhibitor) Perkin Elmer Wizard TBG Siemens TBhCG2 Unicel Testosterone Abbott Architect Beckman Coulter Access Unicel Roche cobas Elecsys Modular E Siemens Centaur TGAB Brahms Kryptor Page 12 of 14

14 ThCG Siemens Centaur Thyroglobulin BRAHMS Kryptor In house AutoDelfia Roche Modular E Siemens Immulite TNF alpha Immulite Tobramycin Centaur Toxo IgG Diasorin Liaison Toxo IgM Liaison Roche cobas Transaminase IgA Phadia Immunocap Transaminase IgG Immunocap TRANSGLU Immunocap TRAS Roche Modular E RSR Limited Unknown: Kitname: Trab ELISA 3A Triiodothyronine-reaction Siemens Centaur Troponin I Abbott Architect Beckman Coulter Access Unicel Ortho Vitros Radiometer AQT90 Flex 1 0 Siemens Centaur Stratus CS Troponin T Roche cobas Elecsys h Modular E Troponin T-hs cobas Elecsys Modular E Tryptase Phadia Immunocap TSH Abbott Architect Unicel Ortho Vitros Perkin Elmer AutoDelfia Roche cobas Elecsys Modular E Siemens Centaur Immulite Tumor necrosis factor alpha BioRad BioPlex T-Uptake Roche cobas Page 13 of 14

15 T-Uptake Siemens Centaur U1RNP-ab Phadia Immunocap Valproic Acid Abbott Architect Olympus Olympus Roche Modular P Siemens Immulite Vancomycin Abbott Architect Siemens Centaur Vitamin B12 Abbott Architect Beckman Coulter Access Unicel Roche cobas Elecsys Modular E Siemens Centaur Vitamin D Diasorin Liaison Vttg - IgA Phadia Immuno VWF:Ag Siemens BCS XP Page 14 of 14