Malene Laursen Speciallæge i ortopædkirurgi Ph.d., Forskningsansvarlig Overlæge

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1 Malene Laursen Speciallæge i ortopædkirurgi Ph.d., Forskningsansvarlig Overlæge ANSÆTTELSER Forskningsansvarlig overlæge, CPK, Regionshospital Silkeborg, HEM Overlæge, Ortopædkirurgisk Afdeling rygsektionen, CPK, RH Silkeborg, HEM 2006 Afdelingslæge, ortopædkirurgisk afdeling, rygsektionen, Aalborg 2005 Afdelingslæge, ortopædkirurgisk afdeling, Silkeborg Central Sygehus Reservelæge, kursusstilling (III), ortopædkirurgisk afdeling, Silkeborg Central Sygehus 2001 Kursusstilling (II), ortopædkirurgisk afdeling, Aalborg 2000 Klinisk assistent, rygsektionen, ortopædkirurgisk afdeling E, Aarhus Universitets Hospital 1999 Intro, ortopædkirurgisk afdeling, Silkeborg Central Sygehus 1999 Intro, ortopædkirurgisk afdeling E, Aarhus Amts Sygehus 1997 Klinisk assistent og ph.d.-stud., rygsektionen, ortopædkirurgisk afdeling E, Århus Universitetshospital, Sundhedsvidenskabelig Fakultet, Aarhus Universitet 1997 Reservelæge, ortopædkirurgisk afdeling, Randers Centralsygehus 1996 Cont. intro, organkirurgisk afdeling, Randers Centralsygehus 1996 Klinisk assistent, ortopædisk Hospital Aarhus v. Prof. Cody Bünger 1995 Intro, organkirurgisk afdeling, Randers Centralsygehus 1994 Intro, ortopædkirurgisk afdeling, Randers Centralsygehus 1994 Turnus-reservelæge, Tranbjerg lægepraksis 1993 Turnus-reservelæge, medicinsk afdeling, Randers Centralsygehus 1993 Turnus-reservelæge, ortopædkirurgisk afdelig, Randers Centralsygehus 1992 Reservelæge, vikar, Kirurgisk afdeling, Hobro Sygehus 1992 Reservelæge, vikar, ortopædkirurgisk afdeling, Viborg Sygehus UDDANNELSER 2005 Speciallæge, ortopædisk kirurgi 2001 Ph.d., Aarhus Universitet 1992 Cand. med., Aarhus Universitet 1982 Matematisk-naturfaglig student, Tørring Gymnasium PUBLIKATIONER Videnskabelige artikler Andersen T, Christensen FB, Laursen M, Lund-Olesen L, Gelineck J, Bünger C. (2003) In vitro osteoblast proliferation as a predictor for spinal fusion mass Spine J., 3(4) P Laursen M, Christensen FB, Lind M, Hansen ES, Høy K, Gelineck J, Bünger C (2003) In vitro osteoblast-like cell metabolism in spondylodesis- a tool that may predict spinal fusion, Acta Orthop Scand (Acta Orthop Scand, 74(6) P ) 1

2 Christensen FB, Stender HE, Laursen M, Thomsen K, Bünger C (2003) Supplemental pedicle-screw implementation did not improve long-term functional outcomes after spinal arthrodesis The Journal of Bone Joint Surgery American, 2(2) P 385 Lind M, Jensen TB, Laursen M, Overgaard S, Søballe K, Bünger C (2003) Klinisk anvendelse af knoglesubstitutter inden for ortopædkirurgi Ugeskrift for Læger, 165(39), P , Review Laursen M, Christensen FB, Bünger C, Lind M (2003) Optimal handling of fresh cancellous bone graft: different peroperative storing techniques evaluated by in vitro osteoblast-like cell metabolism Acta Orthop Scand Scand., 74(4), P Li H, X Zou, Laursen M, Egund N, Lind M, Bünger C ( 2002) The influence of intervertebral disc tissue on anterior spinal interbody fusion: an experimental study on pigs Eur Spine, 11, P Christensen FB, Hansen ES, Laursen M, Thomsen K, Bünger C (2002) Long-term functional outcome of pedicle screw instrumentation as a support for posterolateral spinal fusion: Randomized clinical study with a 5-year follow-up Spine 15;27(12), P Andersen MS T, Christensen FB, Laursen M, Hoy K, Hansen ES, Bünger C (2001) Smoking as a predictor of negative outcome in lumbar spinal fusion Spine 26(23), P Christensen FB, Laursen M, Gelineck J, Hansen ES, Bünger C (2001) Posterolateral spinal fusion at nonintended levels due to bone graft migration Acta Orthop Scand., 72(4), P Christensen FB, Laursen M, Gelinick J, Eiskjær S, Thomsen K, Bünger C (2001) Interobsever and intraobserver agreement of radiograph interpretation with and without pedicle screw implants: The need for a detailed classification system in posterolateral spinal fusion Spine 26(5), P Haisheng L, Laursen, M, Lind M, Shangtai S, Bünger C (2002) The influence of human intervertebral disctissue on the metabolism of osteoblast like cells Acta Ortopaedica Scandinavica, 71(5), P Lind M, Laursen M, Overgaard S, Jensen TB, Søballe K, Bünger C (2000) Stimulation af knogleheling med vækstfaktorer indenfor Ortopædkirurgien Ugeskrift for læger, 162(47), P Bünger C, Laursen M, Hansen ES, Helmvig P, Høy K, Neumann P, Christensen FB (1999) An Algorithmn for the surgical treatment of spinal metastasis Current opinion in orthopedics 1999, 10, P Laursen M, Høy K, Hansen ES, Bünger C (1999) Recombinant bone morphogenetic protein-7 as an intracorporal bone growth stimulator in unstable burst fractures in humans: Preliminary results Eur Spine J. 8(6), P Laursen M, Thomsen K, Eiskjær S, Bünger, C (1999) C Functional Outcome after Partial Reduction and 360 degrees Fusion in grade III-V Spondylolisthesis in Adolescent and Young Patients J Spinal Disord 12(4), P Laursen MS, Eiskjær FB, Christensen K, Thomsen, Bünger C (1999) Resultat efter operativ behandling af ustabile thoracolumbale columna frakturer Ugeskrift for læger 161(13), P

3 Afhandling Laursen, M (2001) Predictive Parameters of Autogenous Iliac Crest Bone Graft for Lumbar Spinal Fusion: Quantitative and In vitro Qualitative Aspects Faculty of Health Sciences, University of Aarhus Konference abstracts Laursen M (2005) Smerter i hofte, knæ og skulder. Årsag og behandling Gigtforening, 27. januar, Horsens Laursen M (2004) Slidgigt i ryggen, Faktorer med betydning for resultatet ved operation Gigtforeningen, 29. januar, Horsens Petruskevicius J, Laursen M, Lemche P, Eiskjær S (2002) The Walter Reed Visual Assessment Scale: Is the scale sensitive to changes in curve magnitude induced by surgery Dansk Ortopædisk Selskab 26. oktober, København Laursen M, Lemke P, Kazlauskas A, Fedders O, Eiskjær S (2002) Transvertebral HMA screws for high grade spondylolisthesis Dansk Ortopædisk Selskab, 3-4. maj, Aalborg Laursen M, Lemke P, Kazlauskas A, Fedders O, Eiskjær S (2002) Transvertebral HMA screws for high grade spondylolisthesis Effort travelling fellows, maj, Aalborg Lemke P, Laursen M et al. (2002) Transvertebral HMA screws for high grade spondylolisthesis Nordisk Scoliosis Society, 1. juni, Oslo Laursen M (2002) Predictive parameters of autologous iliac bone graft for spinal fusion. Quantitative and in vitro qualitative aspects Guest speeker, januar, Sälen, Sverige Bünger C, Hansen ES, Høy K, Helmig, Lindblad BE, Neumann P, Niedermann B, Boeing I, Laursen M, Christensen FB (2001) Lumbar spine fusion Dansk Ortopædisk Selskab, 4-5. maj, Aarhus Laursen M, Christensen FB, Hansen ES, Høy K, Gelineck J, Niedermann B, Helmig P, Bünger C (2001) Fusion rates in posterolateral spondylodesis surgery are highly dependent on the quantity of autograft used Dansk Ortopædisk Selskab, 4-5. maj, Aarhus Haisheng L, Laursen M, Xuenong Z, Stender M, Bünger C (2001) Enhancement of anterior spinal fusion with OP-1 Dansk Ortopædisk Selskab, 4-5. maj, Aarhus Haisheng L, Xuenong Z, Laursen M, Lind M, Bünger C (2001) The influence of intervertebral disc tissue on spinal interbody fusion Dansk Ortopædisk Selskab, 4-5. maj, Aarhus Christensen FB, Hansen ES, Høy K, Helmig P, Lindblad BE, Neumann P, Niedermann B, Laursen M, Bünger C (2001) A randomized prospective study of circumferential fusion versus posterolateral fusion Eurospine, 4-8. september, Göteborg Laursen M, Christensen FB, Hansen ES, Høy K, Gelineck J, Niedermann B, Helmig P, Bünger C (2001) Fusion rates are highly dependent on the quantity of auto-graft in instrumented posterolateral lumbar fusions. A prospective clinical study SICOT, 30. august - 1. september, Paris, Frankrig 3

4 Bünger C, Hansen ES, Høy K, Neumann P, Niedermann B, Lindblad BE, Helmig P, Laursen M, Christensen FB (2001) Lumbar spine fusion. A randomized prospective study of circumferential fusion with the ALIF brantigan cage versus instrumented posterolateral fusion with titanium CDI Nordic Spinal Deformity Society, juni, Silkeborg Laursen M, Christensen FB, Hansen ES, Høy K, Gelineck J, Niedermann, Helmig P, Bünger C (2001) Fusion rates are highly dependent on the quantity of auto-graft in instrumented posterolateral lumbar fusions. A prospective clinical study Nordic Spinal Deformity Society juni, Silkeborg Bünger C, Hansen ES, Høy K, Neumann P, Niedermann B, Lindblad BE, Helmig P, Laursen M, Christensen FB (2001) Lumbar spine fusion. A randomized prospective study of circumferential fusion with the ALIF brantigan cage versus instrumented posterolateral fusion with titanium CDI British Scoliosis Society, 7-9. marts, Edinburgh Laursen M, Christensen FB, Hansen ES, Høy K, Gelineck J, Niedermann, Helmig P, Bünger C (2001) Fusion rates are highly dependent on the quantity of auto-graft in instrumented posterolateral lumbar fusions. A prospective clinical study British Scoliosis Society, 7-9. marts, Edinburgh Christensen FB, Andersen T, Laursen M, Neumann P, Hansen ES, Bünger C. (2000) Smoking predicts inferior functional outcome after lumbar spinal fusion Poster præsentation, ISSLS, april Sydney, Australia Christensen FB, Laursen M, Gehrchen PM, Lund-Olsen L, Gelineck J, Bünger C (2000) Pedicle screw instrumentation increases the posterolateral spinal fusion mass Andersen T, Christensen FB, Laursen M, Hansen ES, Høy K, Bünger C (2000) Candidates for spinal fusion moke more than the background population Should a systematic smoking cessation programme be considered? Dansk Ortopædisk Selskab, 6. maj, Odense Haisheng L. Xuenong Z, Laursen M, Changtai S, Lind M, Bünger C (2000) The influence of intervertebral disc tissue on spinal interbody fusion Center for Vækst og Regenration, 12. april, Aarhus Haishen L, Laursen M, Changtai S, Lind M and Bünger C (2000) In vitro study of intervertebral disc tissue on the metabolism of osteoblast like cells Center for Vækst og Regenration, 11. april, Aarhus Christensen FB, Laursen M, Gehrchen PM, Lund-Olesen L, Gelineck J, Bünger C (2000) Pedicle screw instrumentation increases the posterolateral spinal fusion mass World Spine, Berlin Andersen T, Christensen FB, Laursen M, Neumann P. Hansen ES, Høy K, Bünger C (2000) Preoperative smoking increases risk of non-union and dissatisfaction in lumbar spinal fusion patients Worldspine, Berlin Haishen L, Laursen M, Changtai S, Lind M, Bünger C (2000) In vitro study of intervertebral disc- tissue on the metabolism of osteoblast like cells SIROT, maj, Shanghai, Kina Haishen L, Xuenong Z, Laursen M, Changtai S, Lind M, Bünger C (2000) The influence of intervertebral disc tissue on spinal interbody fusion. An experimental study in pigs SIROT, maj, Shanghai, Kina 4

5 Andersen T, Christensen FB, Laursen M, Helmvig P, Høy K, Niedermann, Bünger C (2000) Candidates for spinal fusion smoke significantly more than the background population Poster præsentation, ISSLS, april, Sydney, Australia Christensen FB, Laursen M, Gelinick J, Eiskjaer S, Thomsen K, Bünger C. (1999) Spinal fusion on nonintended levels due to bone graft migration Poster præsentation, ISSLS, juni, Honolulu, Hawaii Christensen FB, Laursen M, Gelinick J, Eiskjaer S, Thomsen K, Bünger C (1999) Reliability in xray interpretation of the posterolateral spinal fusion, with and without pedicle screw implants, when using a detailed classification system Poster præsentation, ISSLS, juni, Honolulu, Hawaii Laursen M, Sun S, Li H, Overgaard S, Bünger C (1999) The Influence of Disc-tissue on Bone Graft Healing Poster præsentation, ISSLS, juni, Honolulu, Hawaii Christensen FB, Laursen M, Gelinick J, Eiskjær SP, Thomsen K, Bünger C (1999) Spinal Fusion on Nonintended Levels due to bone Graft migration Poster præsentation, SIROT, april, Sydney, Australien Christensen FB, Laursen M, Gelinick J, Eiskjaer S, Thomsen K, Bünger C (1999) Reliability in xray interpretation of the posterolateral spinal fusion, with and without pedicle screw implants, when using a detailed classification system Poster præsentation, SIROT, april, Sydney, Australien Laursen M, Høy K, Gelineck J, Hansen ES, Christensen FB, Bünger C (1999) BMP-7 as an intracorporal bone growth stimulator. Dissapointing preliminary results Poster præsentation, SIROT, april, Sydney, Australien Laursen M, Høy K, Hansen ES, Gelineck J, Christensen FB, Bünger C (1999) BMP-7 som Intrakorporal knogle vækst stimulator ved unstabile thoracolumbar Burst Frakturer Center for Vækst og Regenration, 18. november, Aarhus Christensen FB, Andersen T, Laursen M, Helmvig P, Høy K, Niedermann B (1999) Candidates for spinal fusion smoke significantly more than the background population Dansk Rygkirurgisk Selskab (DRKS), 14. oktober, Skejby Christensen FB, Andersen T, Laursen M, Neumann P, Hansen ES, Bünger C (1999) Smoking predicts inferior functional outcome after lumbar fusion Dansk Rygkirurgisk Selskab (DRKS), 14. oktober, Skejby Christensen FB, Laursen M, Gelinick J, Hansen ES, Bünger C (1999) Spinal fusion on non-intended levels due to bone graft migration Dansk Ortopædisk Selskab, 7-8. maj, Middelfart Christensen FB, Laursen M, Dalstra M, Sejling F, Overgaard S, Bünger CE (1999) Titanium enhances bonepedicle screw fixation. Mechanical and histomorphometrical results of titanium versus stainless steel EuroSpine, September, München, Tyskland Christensen FB, Laursen M, Gelineck J, Eiskjær S, Thomsen K, Bünger CE (1999) Reliability in evaluating lumbar spinal fusion mass, with and without pedicle screw implants by use of plain x-rays EuroSpine, september, München, Tyskland 5

6 Bünger C, Laursen M, Hansen ES, Helmvig P, Høy K, Niederman B, Neumann P (1999) Combined surgical strategy in the treatment of metastases of the spine EuroSpine, september, München, Tyskland Laursen M, Høy K, Hansen ES, Gelenick J, Christensen FB, Bünger C (1999) BMP-7 as an Intracorporal Bone Growth Stimulator in Unstable Spine Fractures ISSLS (International Society for The Study of The Lumbar Spine, juni, Honolulu, Hawaii Bünger C, Laursen M et al. (1999) An Alogrithm for the Treatment of Spinal Metastasis. 1 st Basic Course in Spine Surgery Nordic Orthopedic Federation, Sälen, Sverige Christensen FB, Laursen M, Gelineck J, Eiskjær S, Thomsen K, Bünger C (1999) Reliability in x-ray interpretation of the posterolateral spinal fusion, with and without pedicle screw, when using a detailed classification system Dansk Ortopædisk Selskab, 7-8. maj, Middelfart Bünger C, Laursen M, Hansen ES, Helmvig P, Niedermann B, Høy K, Christensen FB (1999) Kirurgisk strategi i behandlingen af columna metastaser Dansk Ortopædisk Selskab, 7-8. maj, Middelfart Laursen M, K Høy, ES Hansen, J Gelineck, FB Christensen and Bünger C (1999) BMP-7 som Intrakorporal knogle vækst stimulator ved unstabile thoracolumbar Burst Frakturer Dansk Ortopædisk Selskab, 7-8. maj, Middelfart Laursen M, Høy K, Gelineck J, Hansen ES, Christensen FB, Bünger C (1999) BMP-7 as an intracorporal bone growth stimulator Poster præsentation, EFFORT, 3-8. juni, Bruxelles, Belgien Laursen M, Høy K, Gelineck J, Hansen ES, Christensen FB, Bünger C (1998) Preliminary Results after Transpedicular BMP-7 Transplantation in Unstable Spine Fractures Poster præsentation, NOF, 2-6. juni, København Bünger C, Nygaard L, Christensen FB, Hansen ES, Laursen M, Haisheng L (1998) Functional Outcome after Surgical Treatment of Idiopatic Scoliosis in the Adult STRYKER SPINAL SYMPOSIUM, september, Korea Bünger C, Hansen ES, Høy K, Helmvig P, Niedermann B, Laursen M, Dresler W (1998) Treatment of Kyphosis Nordic Scoliosis Society, august, Saltsjöbaden, Sverige Laursen M, Høy K, Gelineck J, Hansen ES, Christensen FB, Bünger C (1998) Preliminary results after transpedicular BMP-7 transplantation in unstable spine fractures Nordic Scoliosis Society, august, Saltsjöbaden, Sverige Bünger C, Laursen M, ES Hansen, Høy K (1998) Combined Surgical Strategy in the Treatment of Metastases of the spine EFFOR, 1-2. juni, København Laursen M, Thomsen K, Hansen ES, Bünger C (1998) High Grade Spondylolisthesis treated with 360 degree fusion The 9 th SICOT Traninees Meeting, 2-3. juni, København 6

7 Laursen M, Høy K, Gelineck J, Hansen ES, Christensen FB, Bünger CE(1998) Preliminary results after transpedicular BMP-7 transplantation in unstable spine fractures The 9 th SICOT Traninees Meeting, 2-3. juni, København Laursen M, Thomsen K, Hansen ES, Bünger C (1998) Functional and Radiological Outcome in High Grade Spondylolisthesis treated with Partial Reduction and Circumferential Fusion. A 2 year follow-up in 11 patients Travelling Fellows, 6. februar, Skejby Laursen M, Høj K, Bünger CE (1998) Results regarding Clinical Application of The BMP-7 device Travelling Fellows, 6. februar, Skejby Bünger C, Christensen FB, Hansen ES, Høy K, Laursen M, Eiskjær S(1998) Pseudoarthrosis of The Lumbar Spine. REVISON SURGERY Consensus conference GICD, januar, Cortina d Àmpezzo, Italien Bünger C, Laursen M, Eiskjær S, Thomsen K, Seiling F, Hansen ES (1997) Operativ behandling af ekstradurale columna tumorer Dansk Ortopædisk Selskab, 1-3. maj, Aarhus Bünger C, Laursen M, Thomsen K, Eiskjær S (1997) Partial reduction and 360 degrees fusion in grade III-V spondylolisthesis in adolescent and young patients 2nd STRYKER SPINAL SYMPOSIUM Laursen M, Thomsen K, Eiskjær S, Bünger C (1996) Partiel reduction og 360 graders fusion i behandlingen af grad III-V spondylolistese Dansk Ortopædisk Selskab, København Bünger C. Laursen M, Eiskjær S, Thomsen K, Seiling F, Hansen ES (1996) Treatment strategy in extradural spine tumors European association of Neuro-Surgeons (EANS), september, Rebil Christensen FB, Lind M, Thomsen K, Eiskjær S, Laursen M, Bünger C (1996) Predictability of Spinal fusion by Autologous Bone Culture Nordisk Scolioseforenings årsmøde, august, København Laursen M, Thomsen K, Eiskjær S, Bünger C (1996) Partial reduction and 360 degrees fusion in severe Spondylolisthesis grade III-V in young and adolescent Nordisk Scolioseforenings årsmøde, august, København Christensen FB, Thomsen K, Eiskjær S, Laursen M, Gelineck J, Bünger C (1995) Inter-/intra-observer variation in the evaluation of radiographic healing after posterolateral lumbar Spine fusion (PLIF) Nordic Ortopaedic Research Society, oktober, København Laursen M, Eiskjær S, Christensen FB, Christensen JØ, Thomsen K, Bünger C (1995) 1-års resultat efter osteosyntese af thoracolumbale columna frakturer Dansk Ortopædisk Selskab, oktober, København Knudsen MH, Laursen M, Bak B, Hvid I, Andreassen TT (1994) En kaninmodel til lokal intraarteriel infusion af farmaka eller hormoner Dansk Ortopædisk Selskab UNDERVISNING/KURSUSARRANGØR 2009 Studenterundervisning, ortopædkirurgisk afdeling, Regionshospitalet Silkeborg 2009 Undervisnings & forsknings-aftenmøder, ortopædkirurgisk afdeling, Regionshospitalet Silkeborg 7

8 2005 Undervisnings & forsknings-aftenmøder, ortopædkirurgisk afdeling, Regionshospitalet Silkeborg 2005 Posterior Spine Surgery. Theory and Practical exercieses on pigs. (Medtronic) Institut for Klinisk og Eksperimentel Forskning, Skejby, Aarhus Universitets Hospital. (arrangør) 2003 Undervisnings & forsknings-aftenmøder, ortopædkirurgisk afdeling, Regionshospitalet Silkeborg 2003 Spine Instrumentation, Practical exercises on pigs, (Medtronic) Institut for Klinisk og Eksperimentel Forskning, Skejby, Aarhus Universitets Hospital (arrangør) 2002 Konfrontations undervisning, rygkirurgi, ortopædkirurgisk afdeling, Aalborg 2000 Konfrontations undervisning, 7. semester ortopædkirurgisk klinikker, Aarhus Universitets Hospital 1999 SAKS, Skejby (medarrangør) Konfrontations undervisning, 7. semester ortopædkirurgisk klinikker, Aarhus Universitets Hospital 1997 Færdighedskursus, Institut for Klinisk og eksperimentel forskning, Aarhus Universitets Hospital (medarrangør) PEER-REVIEW Acta Ortopaedica Scand 8