Årsrapport 2016 Registrering af publikationer og aktiviteter

Transkript

1 Årsrapport 2016 Registrering af publikationer og aktiviteter Den fokuserede forskningsenhed i Reumatologi, Sygehus Sønderjylland/Kong Christian X s Gigthospital, Institut for Regional Sundhedsforskning, Syddansk Universitet, Danmark

2 Indhold Indhold side 2 1. Medarbejdere side Ansatte ved Forskningsenheden ved Kong Christian X s Gigthospital side Forskningsenhedens brugerråd side 3 2. Eksterne bevillinger og donationer side 3 3. Artikler i tidsskrifter side peer reviewede artikler side Øvrige artikler ikke peer reviewede side 9 4. Konferencebidrag: Abstracts/postere/videnskabelige præsentationer side Abstracts side Postere side Videnskabelige præsentationer side Ph.d. forsvar side Andre forsknings- og formidlingsaktiviteter side Foredrag side Deltagelse i workshop, seminar, kursus, konference side Deltagelse i råd, nævn, udvalg og netværk side Optræden i massemedier side Løbende redaktionsarbejde side Formand for bedømmelsesudvalg side Medlem af bedømmelsesudvalg side 20 2

3 1 Medarbejdere 1.1 Ansatte ved Forskningsenheden ved Kong Christian X s Gigthospital Kim Hørslev-Petersen, professor, dr. med. Oliver Hendricks, overlæge, ph.d., forskningslektor Jette Primdahl, RN, MHH, ph.d., lektor Ulrich Weber, overlæge, lektor Alice Ashouri Christiansen, læge, ph.d. studerende Helle Feddersen, sygeplejerske, cand. pæd. soc., ph.d. studerende Dorota Küttel, læge, ph.d. studerende Pia Veje, sygeplejerske, cand. cur., ph.d. studerende Anette Hvenegaard Kjeldgaard, læge Melpomeni Varvounis, læge Karen Mølbæk, cand. mag., forskningsassistent Randi Petersen, RN, SD, forskningssygeplejerske Kirsten Frøhlich, forskningssekretær 1.2 Patientrepræsentanter i forskningsenhedens brugerråd Anne Marie Holm Susanne Wogensen Mette Fravsbøl Preben Delfs Willy Fick Peter Bindeballe Else Gehrke Hansen Torben Hejlesen Liselotte Mølgaard 2 Eksterne bevillinger og donationer Jette Primdahl har modtaget kr. fra Gigtforeningen til projektet: Opfølgning efter screening for risiko for hjerte-kar-sygdom hos patienter med inflammatorisk gigt - går patienter med høj risiko til egen læge efterfølgende og har deres socioøkonomiske status betydning? Jette Primdahl har modtaget kr. fra Gigtforeningens Forskningsråd til projektet: Validation of the Danish version of the Bristol Rheumatoid Arthritis Fatigue Multi-Dimensional Questionnaire (BRAF MQD) and the Bristol Rheumatoid Arthritis Fatigue Numerical Rating Scales (BRAF NRS V2) 3

4 Helle Feddersen har modtaget kr. fra IRS s kursus- og rejsepulje som tilskud til rejse og overnatning i forbindelse med studieophold. 3 Artikler i tidsskrifter 3.1 peer reviewede artikler 1. Hand bone loss in early rheumatoid arthritis during a methotrexate-based treat-to-target strategy with or without adalimumab-a substudy of the optimized treatment algorithm in early RA (OPERA) trial. Ørnbjerg LM, Østergaard M, Jensen T, Hørslev-Petersen, K, Stengaard- Pedersen K, Junker P, Ellingsen T, Ahlquist P, Lindegaard H, Linauskas A, Schlemmer A, Dam, MY, Hansen I, Lottenburger T, Ammitzbøll CG, Jørgensen A, Krintel SB, Raun J, Hetland ML; OPERA Study Group., Slot O, Nielsen LK, Skjødt H, Majgaard O, Lorenzen T, Horn HC, Kowalski M, Johansen IL, Pedersen PM, Manilo N, Bliddal H., Clin Rheumatol Dec 5. [Epub ahead of print] PubMed PMID: Cardiovascular risk profiles in a hospital-based population of patients with psoriatic arthritis and ankylosing spondylitis: a cross-sectional study. Nissen CB, Hørslev-Petersen, K, Primdahl J. Rheumatol Int Nov 26. [Epub ahead of print] PubMed PMID: Effect of a treat-to-target strategy based on methotrexate and intra-articular betamethasone with or without additional cyclosporin on MRI-assessed synovitis, osteitis, tenosynovitis, bone erosion, and joint space narrowing in early rheumatoid arthritis: results from a 2-year randomized double-blind placebo-controlled trial (CIMESTRA). Møller-Bisgaard S, Ejbjerg BJ, Eshed I, Hørslev-Petersen, K, Hetland ML, Jurik AG, Thomsen H, Torfing T, Stengaard-Pedersen K, Junker P, Krogh NS, Lottenburger T, Ellingsen T, Andersen LS, Skjødt H, Svendsen AJ, Tarp U, Hansen IT, Pødenphant J, Pedersen JK, Lindegaard H, Hanson LG, Vestergaard A, Glinatsi D, Østergaard M. Scand J Rheumatol Oct 24:1-11. [Epub ahead of print] PubMed PMID: Limited reliability of radiographic assessment of sacroiliac joints in patients with suspected early spondyloarthritis. Christiansen AA, Hendricks O, Kuettel D, Hørslev-Petersen, K, Jurik AG, Nielsen S, Rufibach K, Loft AG, Pedersen SJ, Hermansen LT, Østergaard M, Arnbak B, Manniche C, Weber U. J Rheumatol Oct 15. pii: jrheum [Epub ahead of print] PubMed PMID: Using an electronic platform interactively to improve treatment outcome in patients with rheumatoid arthritis: new developments from the DANBIO registry. Hetland ML, Krogh NS, Hørslev-Petersen, K, Schiøttz-Christensen B, Sørensen IJ, Dorte Vendelbo J. Clin Exp Rheumatol Sep-Oct;34 Suppl 101(5): Review. PubMed PMID: No diagnostic utility of antibody patterns against Klebsiella pneumoniae capsular serotypes in patients with axial spondyloarthritis vs. patients with non-specific low back pain: a crosssectional study. Hermansen LT, Loft AG, Christiansen AA, Munk HL, Gilbert L, Jurik AG, Arnbak 4

5 B, Manniche C, Weber U, Østergaard M, Pedersen SJ, Barington T, Junker P, Hørslev-Petersen, K, Hendricks O. Scand J Rheumatol Sep 7:1-7. [Epub ahead of print] PubMed PMID: A disintegrin and metalloprotease-17 and galectin-9 are important regulators of local 4-1BB activity and disease outcome in rheumatoid arthritis. Nielsen MA, Andersen T, Etzerodt A, Kragstrup TW, Rasmussen TK, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen, K, Junker P, Østergaard M, Hvid M, Moestrup SK, Deleuran B. Rheumatology (Oxford) Oct;55(10): doi: /rheumatology/kew237. PubMed PMID: Multifactorial intervention to prevent cardiovascular disease in patients with early rheumatoid arthritis: protocol for a multicentre randomized controlled trial. Svensson AL, Christensen R, Persson F, Løgstrup BB, Giraldi A, Graugaard C, Fredberg U, Blegvad J, Thygesen T, Hansen IM, Colic A, Bagdat D, Ahlquist P, Jensen HS, Hørslev-Petersen, K, Sheetal E, Christensen TG, Svendsen L, Emmertsen H, Ellingsen T. BMJ Open Apr 20;6(4):e doi: /bmjopen PubMed PMID: ; PubMed Central PMCID: PMC The discriminative value of inflammatory back pain in patients with persistent low back pain. Arnbak B, Hendricks O, Hørslev-Petersen, K, Jurik AG, Pedersen SJ, Østergaard M, Hermansen LT, Loft AG, Jensen TS, Manniche C. Scand J Rheumatol Jul;45(4): doi: / PubMed PMID: The interleukin-20 receptor axis in early rheumatoid arthritis: novel links between diseaseassociated autoantibodies and radiographic progression. Kragstrup TW, Greisen SR, Nielsen MA, Rhodes C, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen, K, Junker P, Østergaard M, Hvid M, Vorup-Jensen T, Robinson WH, Sokolove J, Deleuran B. Arthritis Res Ther Mar 11;18:61. doi: /s PubMed PMID: ; PubMed Central PMCID: PMC Changes in soluble CD18 in murine autoimmune arthritis and rheumatoid arthritis reflect disease establishment and treatment response. Kragstrup TW, Jalilian B, Keller KK, Zhang X, Laustsen JK, Stengaard-Pedersen K, Hetland ML, Hørslev-Petersen, K, Junker P, Østergaard M, Hauge EM, Hvid M, Vorup-Jensen T, Deleuran B. PLoS One Feb 5;11(2):e doi: /journal.pone PubMed PMID: ; PubMed Central PMCID: PMC Associations between spondyloarthritis features and magnetic resonance imaging findings: A cross-sectional analysis of 1,020 patients with persistent low back pain. Arnbak B, Grethe Jurik A, Hørslev-Petersen, K, Hendricks O, Hermansen LT, Loft AG, Østergaard M, Pedersen SJ, Zejden A, Egund N, Holst R, Manniche C, Jensen TS. Arthritis Rheumatol Apr;68(4): doi: /art PubMed PMID: Clinical and radiographic outcome of a treat-to-target strategy using methotrexate and intraarticular glucocorticoids with or without adalimumab induction: a 2-year investigator-initiated, 5

6 double-blinded, randomised, controlled trial (OPERA). Hørslev-Petersen, K, Hetland ML, Ørnbjerg LM, Junker P, Pødenphant J, Ellingsen T, Ahlquist P, Lindegaard H, Linauskas A, Schlemmer A, Dam MY, Hansen I, Lottenburger T, Ammitzbøll CG, Jørgensen A, Krintel SB, Raun J, Johansen JS, Østergaard M, Stengaard-Pedersen K; OPERA Study-Group. Ann Rheum Dis Sep;75(9): doi: /annrheumdis PubMed PMID: Prevalence of degenerative and spondyloarthritis-related magnetic resonance imaging findings in the spine and sacroiliac joints in patients with persistent low back pain. Arnbak B, Jensen TS, Egund N, Zejden A, Hørslev-Petersen, K, Manniche C, Jurik AG. Eur Radiol Apr;26(4): doi: /s PubMed PMID: Are human endogenous retroviruses triggers of autoimmune diseases? Unveiling associations of three diseases and viral loci. Nexø BA, Villesen P, Nissen KK, Lindegaard HM, Rossing P, Petersen T, Tarnow L, Hansen B, Lorenzen T, Hørslev-Petersen, K, Jensen SB, Bahrami S, Lajer M, Schmidt KL, Parving HH, Junker P, Laska MJ. Immunol Res Feb;64(1): doi: /s z. PubMed PMID: ; PubMed Central PMCID: PMC Prediction of treatment response to adalimumab: a double-blind placebo-controlled study of circulating microrna in patients with early rheumatoid arthritis. Krintel SB, Dehlendorff C, Hetland ML, Hørslev-Petersen, K, Andersen KK, Junker P, Pødenphant J, Ellingsen T, Ahlquist P, Lindegaard HM, Linauskas A, Schlemmer A, Dam MY, Hansen I, Horn HC, Jørgensen A, Raun J, Ammitzbøll CG, Østergaard M, Stengaard-Pedersen K, Johansen JS. Pharmacogenomics J Apr;16(2): doi: /tpj PubMed PMID: Diagnostic Delay in Rheumatoid Arthritis: A Qualitative Study of Symptom Interpretation Before the First Visit to the Doctor. Mølbaek K, Hørslev-Petersen, K, Primdahl J. Musculoskeletal Care Mar;14(1): doi: /msc PubMed PMID: EULAR recommendations for cardiovascular disease risk management in patients with rheumatoid arthritis and other forms of inflammatory joint disorders: 2015/2016 update. Agca R, Heslinga SC, Rollefstad S, Heslinga M, McInnes IB, Peters MJ, Kvien TK, Dougados M, Radner H, Atzeni F, Primdahl J, Södergren A, Wallberg Jonsson S, van Rompay J, Zabalan C, Pedersen TR, Jacobsson L, de Vlam K, Gonzalez-Gay MA, Semb AG, Kitas GD, Smulders YM, Szekanecz Z, Sattar N, Symmons DP, Nurmohamed MT. Ann Rheum Dis Jan;76(1): doi: /annrheumdis PubMed PMID: A Difficult Diagnosis: A Qualitative Study of the Daily Lives of Young Men Diagnosed with Ankylosing Spondylitis. Primholdt N, Primdahl J, Hendricks O. Musculoskeletal Care Aug 21. doi: /msc [Epub ahead of print] PubMed PMID: Readability of patient information and consent documents in rheumatological studies. Hamnes B, van Eijk-Hustings Y, Primdahl J. BMC Med Ethics Jul 16;17(1):42. doi: /s PubMed PMID: ; PubMed Central PMCID: PMC

7 21. Nurses' Role in Cardiovascular Risk Assessment and Management in People with Inflammatory Arthritis: A European Perspective. Primdahl J, Ferreira RJ, Garcia-Diaz S, Ndosi M, Palmer D, van Eijk-Hustings Y. Musculoskeletal Care Sep;14(3): doi: /msc PubMed PMID: Ankylosing Spondylitis versus Nonradiographic Axial Spondyloarthritis: Comparison of Tumor Necrosis Factor Inhibitor Effectiveness and Effect of HLA-B27 Status. An Observational Cohort Study from the Nationwide DANBIO Registry. Glintborg B, Sørensen IJ, Østergaard M, Dreyer L, Mohamoud AA, Krogh NS, Hendricks O, Andersen LS, Raun JL, Kowalski MR, Danielsen L, Pelck R, Nordin H, Pedersen JK, Kraus DG, Christensen SR, Hansen IM, Esbesen J, Schlemmer A, Loft AG, Al Chaer N, Salomonsen L, Hetland ML. J Rheumatol Dec 1. pii: jrheum [Epub ahead of print] PubMed PMID: Identification of subgroups of inflammatory and degenerative MRI findings in the spine and sacroiliac joints: a latent class analysis of 1037 patients with persistent low back pain. Arnbak B, Jensen RK, Manniche C, Hendricks O, Kent P, Jurik AG, Jensen TS. Arthritis Res Ther Oct 13;18(1):237. PubMed PMID: ; PubMed Central PMCID: PMC Mycobacterium alsense sp. nov., a scotochromogenic slow grower isolated from clinical respiratory specimens. Tortoli E, Richter E, Borroni E, Cabibbe AM, Capitolo E, Cittaro D, Engel R, Hendricks O, Hillemann D, Kristiansen JE, Mariottini A, Schubert S, Cirillo DM. Int J Syst Evol Microbiol Jan;66(1): doi: /ijsem PubMed PMID: Course of magnetic resonance imaging-detected inflammation and structural lesions in the sacroiliac joints of patients in the randomized, double-blind, placebo-controlled Danish multicenter study of adalimumab in spondyloarthritis, as assessed by the Berlin and Spondyloarthritis Research Consortium of Canada Methods. Pedersen SJ, Poddubnyy D, Sørensen IJ, Loft AG, Hindrup JS, Thamsborg G, Asmussen K, Hendricks O, Nørregaard J, Piil AD, Møller JM, Jurik AG, Balding L, Lambert RG, Sieper J, Østergaard M. Arthritis Rheumatol Feb;68(2): doi: /art PubMed PMID: Measuring impairments of functioning and health in patients with axial spondyloarthritis by using the ASAS Health Index and the Environmental Item Set: translation and cross-cultural adaptation into 15 languages. Kiltz U, van der Heijde D, Boonen A, Bautista-Molano W, Burgos- Vargas R, Chiowchanwisawakit P, Duruoz T, El-Zorkany B, Essers I, Gaydukova I, Géher P, Gossec L, Grazio S, Gu J, Khan MA, Kim TJ, Maksymowych WP, Marzo-Ortega H, Navarro- Compán V, Olivieri I, Patrikos D, Pimentel-Santos FM, Schirmer M, van den Bosch F, Weber U, Zochling J, Braun J. RMD Open Oct 4;2(2):e PubMed PMID: ; PubMed Central PMCID: PMC Controversies in recognition of early disease. Weber U, Jurik AG, Lambert RG, Maksymowych WP. Imaging in Spondyloarthritis: Curr Rheumatol Rep Sep;18(9):58. doi: /s Review. PubMed PMID:

8 28. Predictive validity of the ASAS classification criteria for axial and peripheral spondyloarthritis after follow-up in the ASAS cohort: A final analysis. Sepriano A, Landewé R, van der Heijde D, Sieper J, Akkoc N, Brandt J, Braun J,Collantes-Estevez E, Dougados M, Fitzgerald O, Huang F, Gu J, Kirazli Y, Maksymowych WP, Marzo-Ortega H, Olivieri I, Ozgocmen S, Roussou E, Scarpato S, Sørensen IJ, Valle-Oñate R, Van den Bosch F, van der Horst-Bruinsma I, Weber U, Wei J, Rudwaleit M; ASAS.. Ann Rheum Dis Jun;75(6): doi: /annrheumdis PubMed PMID: Defining active sacroiliitis on MRI for classification of axial spondyloarthritis: update by the ASAS MRI working group. Lambert RG, Bakker PA, van der Heijde D, Weber U, Rudwaleit M, Hermann KG, Sieper J, Baraliakos X, Bennett A, Braun J, Burgos-Vargas R, Dougados M, Pedersen SJ, Jurik AG, Maksymowych WP, Marzo-Ortega H, Østergaard M, Poddubnyy D, Reijnierse M, van den Bosch F, van der Horst-Bruinsma I, Landewé R. Ann Rheum Dis Nov;75(11): doi: /annrheumdis PubMed PMID: Impaired response to treatment with tumour necrosis factor α inhibitors in smokers with axial spondyloarthritis. Ciurea A, Scherer A, Weber U, Exer P, Bernhard J, Tamborrini G, Riek M, Müller RB, Weiss B, Nissen MJ, Kissling R, Michel BA, Finckh A; Rheumatologists of Swiss Clinical Quality Management Program for Axial Spondyloarthritis Ann Rheum Dis Mar;75(3): doi: /annrheumdis PubMed PMID: Does the reason for discontinuation of a first TNF inhibitor influence the effectiveness of a second TNF inhibitor in axial spondyloarthritis? Results from the Swiss Clinical Quality Management Cohort. Ciurea A, Exer P, Weber U, Tamborrini G, Steininger B, Kissling RO, Bernhard J, Scherer A; Rheumatologists of Swiss Clinical Quality Management Program for Axial Spondyloarthritis. Arthritis Res Ther Mar 22;18:71. doi: /s PubMed PMID: ; PubMed Central PMCID: PMC Establishment of age- and sex-adjusted reference data for hand bone mass and investigation of hand bone loss in patients with rheumatoid arthritis treated in clinical practice: an observational study from the DANBIO registry and the Copenhagen Osteoarthritis Study. Ørnbjerg LM, Østergaard M, Jensen T, Hyldstrup L, Bach-Mortensen P, Bøyesen P,Thormann A, Tarp U, Bøhme WP, Lindegaard H, Poulsen UE, Schlemmer A, Graudal N,Rødgaard A, Espesen J, Kollerup GB, Glintborg B, Madsen OR, Jensen DV, Hetland ML. Arthritis Res Ther Feb 24;18:53. doi: /s y. PubMed PMID: ; PubMed Central PMCID: PMC Übersetzung und krosskulturelle Adaptation des ASAS-Gesundheitsindex: Ein ICF-basiertes Instrument zur Erfassung der Funktionsfähigkeit von Patienten mit ankylosierender Spondylitis Kiltz, U., Winter, J., Schirmer, M., Weber, U., Hammel, L., Baraliakos, X., Braun,J. Deutsche 26 okt I : Z Rheumatol. 75;10:

9 34. Petersen, R., Kristiansen, T.M. & Hørslev-Petersen, K. Patientinddragelse i reumatologisk forskning - patient- og forskerperspektiver. Juni Nordisk Sygeplejeforskning. 6, 2, s Øvrige artikler ikke peer reviewede 1. Når læger forsker: Patienter kan også forske. Hørslev-Petersen, K. & Fravsbøl, M. Aug. 2016, Ugeskrift for læger, 16, side Konferencebidrag: Abstracts/posters/videnskabelige præsentationer 4.1 Abstracts 1. Magnetic Resonance Imaging (MRI) joint space narrowing is an independent predictor of radiographic and MRI damage progression in patients with early rheumatoid arthritis. Møller- Bisgaard, S., Ejbjerg, B. J., Eshed, I., Hørslev-Petersen, K., Hetland, M. L., Jurik, A. G., Thomsen, H. S., Torfing, T., Stengaard-Pedersen, K., Junker, P., Steen Krogh, N., Lottenburger, T., Ellingsen, T. J., Smedegaard-Andersen, L., Skjødt, H., Svendsen, A. J., Tarp, U., Hansen, I. T., Pødenphant, J., Kristian Pedersen, J. & 4 flere. Arthritis & Rheumatology, 68, suppl The effect of nurse-led follow-up in rheumatoid arthritis. A systematic review and metaanalysis of randomized controlled trials. Primdahl, J. nov Arthritis & Rheumatology. 68, suppl How do women with rheumatoid arthritis manage their disease, motherhood, and work life? Feddersen, H., Kristiansen, T. M., Andersen, P. T., Hørslev-Petersen, K. & Primdahl, J. The 4th. International global network of public health nursing conference, 19 sep Hand bone loss in early rheumatoid arthritis is independent of adalimumab treatment. A substudy of the Optimized Treatment Algorithm in Early RA (OPERA) TRIAL Ørnbjerg, L. M., Østergaard, M., Jensen, T., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T. J., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. L. & Hetland, M. Juni Annals of the Rheumatic Diseases 75, Supplement Construction of meaningful identities in the context of rheumatoid arthritis (RA) motherhood and paid work: a metasynthesis Feddersen, H., Kristiansen, T. M., Andersen, P. T., Hørslev- Petersen, K. & Primdahl, J. Juni Nordic Conference in Nursing Research, abstractbog side Magnetic resonance imaging joint space narrowing is an independent predictor of radiographic and MRI damage progression in patients with early rheumatoid arthritis Møller-Bisgaard, S., 9

10 Ejbjerg, B. J., Eshed, I., Hørslev-Petersen, K., Hetland, M., Jurik, A. G., Thomsen, H., Torfing, T., Stengaard-Pedersen, K., Junker, P., Steen Krogh, N., Lottenburger, T., Ellingsen, T. J., Smedegaard-Andersen, L., skjødt, H., Svendsen, A. J., Tarp, U., Hansen, I., Pødenphant, J., Pedersen, J. K. & 4 flere. Juni Annals of the Rheumatic Diseases. 75, Supplement 2, 7. No excess mortality in a population-based Danish rheumatoid arthritis cohort from the late pre-biologic era. Pedersen, J. K., Holst, R., Primdahl, J., Svendsen, A. J. & Hørslev-Petersen, K. juni Annals of the Rheumatic Diseases. 75, Supplement 2, s s., THU Soluble CD83 plasma levels are associated with disease activity and course of disease in early rheumatoid arthritis. Kristensen, A. M., Hetland, M., Hørslev-Petersen, K., Junker, P., Østergaard, M., Stengaard-Pedersen, K., Höllsberg, P., Hvid, M. & Deleuran, B. W. juni Annals of the Rheumatic Diseases. 75, Supplement 2, 9. Comprehending human polymicrobial infections for Vector-borne disease diagnostic purposes. Garg, K., Hermansen, L. T., Puttaraska, K., Hendricks, O., Pirttinen, H. & Gilbert, L. April 2016, 26 th ECCMID, Amsterdam. 10. PolyScan: Comprehending Human polymicrobial infections for Vector-borne disease diagnostic purposes. Garg, K., Hermansen, L. T., Puttaraska, K., Hendricks, O., Pirttinen, H. & Gilbert, L. April th ECCMID, Amsterdam. 11. Evaluación de la confiabilidad en la interpretación de las imágenes obtenidas con resonancias magnéticas en una cohorte de pacientes identificados en la comunidad con dolor dorsolumbar de posible origen inflamatorio. Burgos-Vargas, R., Weber, U., Peláez-Ballestas, I., Pedersen, S. J., Julian, B. & Maksymowych, W. P. Feb. 2016, Annual Mexican Congress of Rheumatology. 12. Changes in multi-biomarker disease activity (MBDA) score correlate with changes in established disease activity measurements in patients with early RA from the opera study. Brahe, C. H., Østergaard, M., Johansen, J., Defranoux, N., Hwang, C. C., Bolce, R., Sasso, E., Hørslev- Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A. & 3 flere Annals of the Rheumatic Diseases. 75, Supplement 2, s s., FRI Hla-B27 status is associated with tnf-α inhibitor treatment outcomes in ankylosing spondylitis and non-radiographic axial spondyloarthritis observational cohort study from the nationwide Danbio registry. Glintborg, B., Sørenen, I. J., Østergaard, M., Mahamoud, A. A., Steen Krogh, N., Smedegaard-Andersen, L., Raun, J. L., Hendricks, O., Kowalski, M. R., Danielsen, L., Christensen, S. R., al Chaer, N., Pelck, R., Nordin, H., Pedersen, J. K., Kraus, D. G. A., Jensen Hansen, I. M., Espesen, J., Schlemmer, A., Loft, A. G. & 3 flere Annals of the Rheumatic Diseases. 75, Suppl. 2, 1 s., SAT

11 14. PolyScan: Comprehending human polymicrobial infections for Vector-borne disease diagnostic purposes. Garg, K., Hermansen, L. T., Puttaraska, K., Hendricks, O., Pirttinen, H. & Gilbert, L International Scholarly and Scientific Research & Innovation. 3, 5, 1 s., Three months clinical outcomes from a nationwide non-medical switch from originator to biosimilar infliximab in patients with inflammatory arthritis. Results from the Danbio registry. Glintborg, B., Sørensen, I. J., Jensen, D. V., Steen Krogh, N., Loft, A. G., Colic, A., Espesen, J., Olsen, J., Hendricks, O., Grydehøj, J., Jensen Hansen, I. M., Sørensen, M. V., Chrysidis, S., Manilo, N., Klarlund, M., Andersen, L. S. & Nordin, H Annals of the Rheumatic Diseases. 75, Supplement 2, 4.2 Postere 1. Comparison of tumor necrosis factor alpha inhibitor inhibitor effectiveness in ankylosing spondylitis and nonradiographical axial spondylitis, and the impact of HLA-B27 status. Observational cohort study from the nationwide DANBIO registry. Glintborg, B., Sørensen, I. J., Østergaard, M., Dreyer, L., Abdiweli awil, M., Steen Krogh, N., Hendricks, O., Smedegaard- Andersen, L., Raun, J. L., Kowalski, M. R., Danielsen, L., Pelck, R., Nordin, H., Pedersen, J. K., Kraus, D. G. A., Ringskær Christensen, S., Jensen Hansen, I. M., Esbensen, J., Schlemmer, A., Loft, A. G. & 3 flere. EULAR conference, London, 8. juni Non-medical switch from originator to biosimilar infliximab in patients with inflammatory arthritis - impact on s-infliximab and antidrug-antibodies. Results from the Danish Rheumatologic Biobank and the DANBIO registry. Glintborg, B., Kringelbach, T., Sørensen, I. J., Vendelbo Jensen, D., Loft, A. G., Hendricks, O., Jensen Hansen, I. M., Bolstad, N., Warren, D. J., Gehin, J., Goll, G., Grøn, K., Eng, G., Enevold, C., Nielsen, C. H., Johansen, J. & Hetland, M. L. EULAR conference, London, 8. juni Evolution of MRI inflammation and structural lesions on serial scans over 5 years in patients with ankylosing spondylitis treated with tumor-necrosis-facto-alpha inhibitors. Pedersen, S. J., Weber, U., Said-Nahal, R., Loft, A. G., Christiansen, A., Tvede, N., Kollerup, G., Juul, L., Thamsborg, G., Madsen, O. & Østergaard, M. EULAR conference, London, 8. juni No excess mortality in a population-based Danish rheumatoid arthritis cohort from the late pre-biologic era. Pedersen, J. K., Holst, R., Primdahl, J., Hørslev-Petersen, K. & Svendsen, A. J. EULAR conference, London, 9. juni Changes in multi-biomarker disease activity (MBDA) score correlate with changes in established disease activity measurements in patients with early RA from the opera study. Brahe, C. H., Østergaard, M., Johansen, J., Defranoux, N., Hwang, C. C., Bolce, R., Sasso, E., Hørslev- Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T. J., Ahlquist, P., Lindegaard, H., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A. & 3 flere. EULAR conference, London, 10. juni

12 6. Hand bone loss in early rheumatoid arthritis is independent of adalimumab treatment. A substudy of the optimized treatment algorithm in early RA (OPERA) TRIAL. Ørnbjerg, L. M., Østergaard, M., Jensen, T., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T. J., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. L. & Hetland, M. EULAR conference, London, 10. juni Magnetic resonance imaging joint space narrowing is an independent predictor of radiographic and MRI damage progression in patients with early rheumatoid arthritis. Møller-Bisgaard, S., Ejbjerg, B. J., Eshed, I., Hørslev-Petersen, K., Lund Hetland, M., Jurik, A. G., Thomsen, H., Torfing, T., Stengaard-Pedersen, K., Junker, P., Steen Krogh, N., Lottenburger, T., Ellingsen, T. J., Smedegaard-Andersen, L., Skjødt, H., Svendsen, A. J., Tarp, U., Hansen, I., Pødenphant, J., Pedersen, J. K. & 3 flere. EULAR conference, London, 10. juni The effect of nurse-led follow-up in rheumatoid arthritis. A systematic review and metaanalysis of randomized controlled trials. Primdahl, J. ACR/ARHP 11. nov Magnetic Resonance Imaging (MRI) joint space narrowing is an independent predictor of radiographic and MRI damage progression in patients with early rheumatoid arthritis. Møller- Bisgaard, S., Ejbjerg, B. J., Eshed, I., Hørslev-Petersen, K., Hetland, M. L., Jurik, A. G., Thomsen, H. S., Torfing, T., Stengaard-Pedersen, K., Junker, P., Steen Krogh, N., Lottenburger, T., Ellingsen, T. J., Smedegaard-Andersen, L., Skjødt, H., Svendsen, A. J., Tarp, U., Hansen, I. T., Pødenphant, J., Kristian Pedersen, J. & 4 flere. ACR/ARHP 13. nov Hand bone loss in early rheumatoid arthritis is independent of adalimumab treatment - Results from a randomized controlled clinical trial. Ornbjerg, L. M., Østergaard, M., Jensen, T. D., Hørslev-Petersen, K., Stengaard-Pedersen, K., Junker, P., Ellingsen, T. J., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I. T., Lottenburger, T., Ammitzbøll, C. G., Jørgensen, A., Krintel, S. B., Raun, J. L. & Hetland, M. L. ACR/ARHP 14. nov Multi-Biomarker Disease Activity (MBDA) score and prediction of radiographic progression in a randomized study of patients with early RA treated with methotrexate alone or with adalimumab. Brahe, C. H., Østergaard, M., Johansen, J. S., Defranoux, N. A., Wang, X., Bolce, R. J., Sasso, E. H., Hørslev-Petersen, K., Stengaard-Pedersen, K., Ornbjerg, L. M., Junker, P., Ellingsen, T. J., Ahlquist, P., Lindegaard, H. M., Linauskas, A., Schlemmer, A., Dam, M. Y., Hansen, I. T., Lottenburger, T., Ammitzbøll, C. G. & 4 flere. ACR/ARHP 15. nov Soluble CD206 plasma levels decreases with treatment and reflects anti-tnf-α discontinuation in rheumatoid arthritis. Heftdal, L. D., Stengaard-Pedersen, K., Hetland, M. L., Hørslev- Petersen, K., Junker, P., Østergaard, M., Hvid, M., Deleuran, B. W., Møller, H. J. & Greisen, S. R. ACR/ARHP 15. nov Hip Inflammation MRI Scoring System (HIMRISS) to predict response to hyaluronic acid (HAnox- M-XL) injection in hip osteoarthritis. Deseyne, N., Loeuille, D., Conrozier, T., Weber, U., 12

13 Jaremko, J., Lellouche, H., Maillet, B., Paschke, J., Epstein, J. & Maksymowych, W. P. ACR/ARHP nov In contrast to men, women with nonradiographic axial spondyloarthritis have lower response rates to TNF inhibitors than women with ankylosing spondylitis. U. Weber. The Rheumatologists of Swiss Clinical Quality Management Program for Axial Spondyloarthritis ACR/ARHP nov Radiographic progression and changes in inflammation and structural damage on serial MRI examinations over 5 years in patients with ankylosing spondylitis treated with TNF-Alpha inhibitors. Pedersen, S. J., Weber, U., Said-Nahal, R., Sørensen, I. J., Loft, A. G., Tvede, N., Kollerup, G., Juul, L., Thamsborg, G., Madsen, O. R., Møller, J. M., Balding, L., Jurik, A. G. & Østergaard, M. ACR/ARHP nov Elevated antibody levels against Chlamydia, Borrelia and Ehrlichia cannot discriminate patients with axial spondyloarthritis from non-specific low back pain. Hermansen, L.T., Loft, A. G., Christiansen, A., Gilbert, L., Garg, K., Karvonen, K., Jurik, A. G., Weber, U., Arnbak, B., Manniche, C., Jensen, T. S., Østergaard, M., Pedersen, S. J., Barington, T., Kolmos, H. J., Hørslev- Petersen, K. & Hendricks, O., 25th Meeting of the Poul Ehrlich Society Infectiologie Update, Rostock. 6. Oktober Indirect multiplex enzyme-linked immunosorbent assay for the detection of Chlamydia, Borrelia and Ehrlichia in axial spondyloarthritis. Hermansen, L.T., Loft, A. G., Christiansen, A., Garg, K., Karvonen, K., Arnbak, B., Barington, T., Hørslev-Petersen, K., Hendricks, O, Gilbert, L. 25th Meeting of the Poul Ehrlich Society Infectiologie Update, Rostock. 6. Oktober Videnskabelige præsentationer 1. Comprehending Human Polymicrobial Infections for Vector-Borne Disease Diagnostic Purposes Hermansen, L. T. Hendricks, O. ECCMID april Hvordan håndterer kvinder med leddegigt sygdom, moderskab og arbejdsliv? - et Ph.d.-studie Feddersen, H. Åben Forskerdag april PolyScan: Comprehending Human Polymicrobial Infections for Vector-Borne Disease Diagnostic Purposes. Hendricks, O. ICNT 2016: 18th International Conference on Nephrology and Therapeutics. 23. maj Three months clinical outcomes from a nationwide non-medical switch from originator to biosimilar infliximab in patients with inflammatory arthritis. Hendricks, O. EULAR, 8. juni

14 5. Construction of meaningful identities in the context of rheumatoid arthritis (RA) motherhood and paid work - a metasynthesis. Feddersen, H. Nordic Conference in Nursing Research. 16. juni Readability of patient information and consent documents in rheumatological studies. Primdahl, J. EULAR. 16. juni HLA-B27 status is associated with TNF-alpha inhibitor treatment outcomes in ankylosing spondylitis and non-radiographic axial spondyloarthritis. Hendricks, O. Scandinavian Congress of Rheumatology, SCR sep Three months clinical outcomes from a nationwide non-medical switch from originator to biosimilar infliximab in patients with inflammatory arthritis. Results from the DANBIO registry. Hendricks, O. Scandinavian Congress of Rheumatology, SCR sep How do women with rheumatoid arthritis manage their disease, motherhood, and work life? Feddersen, H. The 4th international global network of public health nursing conference: Bridging the gap in Public Health Nursing. 19. sep Magnetic Resonance Imaging (MRI) Joint Space Narrowing Is an Independent Predictor of Radiographic and MRI Damage Progression in Patients with Early Rheumatoid Arthritis. Hørslev-Petersen, K. ACR/ARHP. 13. nov Years Follow-up of a Danish 2-Year Treat-to-Target RCT in Patients with Early Rheumatoid Arthritis: Baseline Predictors of Functional and Radiographic Outcomes. Hørslev-Petersen, K. ACR/ARHP. 16. nov Ph.d. afhandlinger Molecular biology of infectious agents in the early diagnosis of spondyloarthritis (MICSA). Hermansen, Louise Thuesen, ph.d. forsvar 31. marts Andre forsknings- og formidlingsaktiviteter 6.1 Foredrag Lev et godt liv med leddegigt. Christiansen, A. A. Undervisning af patienter med leddegigt, udbudt i et samarbejde mellem Aabenraa Kommune og Kong Christian X's Gigthospital, Gråsten Nyt om psoriasis artrit og diagnosen spondylartropati (SpA). Hendricks, O. PsA Kredsforeningen Sønderjylland, Rødekro. 23. feb Patientens syn på at deltage i forskning. 14

15 Patientrepræsentant Mette Fravsbøl. DASYS Konference. 16. marts 2016 Utility of MRI to diagnose spondyloarthritis. Weber, U. Danish Imaging Summit Copenhagen. 17. marts 2016 Conventional X-ray of axial spondyloarthritis: How much can we trust pelvic radiographs? Weber, U. Danish Imaging Summit Copenhagen. 17. marts 2016 Patienter med i forskningsteamet. Petersen, R. Dansk Selskab for Interprofessionel læring og Samarbejde i Sundhedsvæsenet. 31. marts 2016 Nyt omkring diagnosen Spondylartropati (rygsøjlegigt?) Hendricks, O. Augustenborg Lægehus. 11. april 2016 Rygsøjlegigt - en update ift. diagnose og moderne behandling. Hendricks, O. Mb. Bechterew Kredsforening, Kolding. 14. april 2016 Tidlig SpA: Har mikrobiologien en ætiologisk betydning? Hendricks, O. The British Society for Rheumatology. 25. april 2016 Sygepleje for patienter med inflammatoriske gigtsygdomme - eksempler på forskning og betydning for klinisk praksis. Primdahl, J. Hvem bestemmer her?: Syddansk Forskningscenter for Klinisk Sygepleje, Aabenraa. 3. juni 2016 Gigt og behandling med fokus på biosimilære stoffer. Christiansen, A. A. Foreningen af unge med gigt (FNUG) landsmøde sep Imaging in Spondyloarthritis: Controversies in Early Disease. Weber, U. Workshop, Reumatologisk afdeling, Odense Universitetshospital. 5. okt Nyt om diagnose Psoriasisartrit og SpA (rygsøjlegigt). Hendricks, O. Psoriasisforeningen, Sønderjyllandskredsen. 6. okt Deltagelse i workshop, seminar, kursus og konference Workshop om MR og ultralyd ved SpA Christiansen, A. A. (Deltager) jan ASAS, Assessment of SpondyloArthritis Weber, U. (Deltager) jan Research Grant Proposals for IRS-ansatte Christiansen, A. A. (Deltager) 13 jan.- 3. feb

16 How to write an abstract Christiansen, A. A. (Deltager) 2. feb How to write an article Christiansen, A. A. (Deltager) april 2016 The British society for Rheumatology Hendricks, O. (Arrangør) april 2016 Hvem bestemmer her? Primdahl, J. (Deltager) 3. juni 2016 Annual European Congress of Rheumatology, EULAR 2016 Hørslev-Petersen, Kim (Deltager) juni 2016 Annual European Congress of Rheumatology, EULAR 2016 Primdahl, Jette (Deltager) Juni 2016 Summer school in Clinical Research Christiansen, A. A. (Deltager) juni th International Congress on Spondylopathies Hendricks, O. (Deltager) sep th International Congress on Spondylopathies Weber, U. (Deltager) sep th Meeting of the Paul-Ehrlich-Society, Infektiologie Update 2016 Hendricks, O. (Deltager) okt Educational Workshop Spondylartropatier Hendricks, O. (Arrangør) 3. nov ACR/ARHP: American College of Rheumatology Weber, U. (Deltager) nov ACR/ARHP: American College of Rheumatology Hørslev-Petersen, Kim (deltager) nov

17 7 Deltagelse i råd, nævn, udvalg og netværk Kim Hørslev-Petersen Medlem af Gigtforeningen siden Medlem af CIMESTRA forskningsnetværk (Medikamentel intervention ved tidlig reumatoid artrit): Sammen med reumatologiske universitetsafdelinger i Århus, Odense, København. Etableret efterår Medlem af specialeråd for reumatologi, Region Syddanmark, siden 2007 Medlem af forskningsråd og forskningsfagligt udvalg, Sygehus Sønderjylland, siden 2009 Deltager i IMAGINE forskningsnetværk. Etableret forår Medlem af skandinavisk forskningsnetværk NORD-STAR Etableret 2010 Medlem af forskningsudvalg. Dansk Reumatologisk Selskab siden 2012 Medlem af Det Svenske Forskningsråd siden 2016 Jette Primdahl Modulansvarlig Kandidat i klinisk sygepleje, Syddansk Universitet, Sundhedsfremme og forebyggelse Medlem af forskningsråd, Sygehus Sønderjylland, siden februar 2009 Deltager i netværk af forskningsinteresserede sygeplejersker i EULAR (European League Against Rheumatism) Formand for bestyrelsen for DIRF (Dansk Interdisciplinært Reumatologisk Forum), bestyrelsesmedlem siden 2009 (optaget i EULARs standing committee 2010) Medlem af Faglig Sammenslutning for Reumatologiske Sygeplejersker (FSRS) siden 2008 Medlem af Dansk Selskab for Sygeplejeforskning Medlem af ph.d.-netværk Syddansk Forskningscenter for Klinisk Sygepleje, Syddansk Universitet Herefter medlem af Netværk for Sygepleje og sundhedsforskning i Region Syddanmark og Region Sjælland Medlem af Gigtforeningen siden 2011 Suppleant for EULAR-repræsentant for European Specialist Nurses Organisation (ESNO) 2016 Oliver Hendricks Medlem af EU Cost act B 16 siden 2004 Medlem af International Society of Non-Antibiotics (ISN) siden 2004 Medlem af International Society of Chemotherapy (ISC) siden 2005 Medlem af Dansk Intern Medicinsk Selskab siden 2005 Medlem af Dansk Reumatologisk Selskab siden 2007 Medlem af PEG (Paul Ehrlich Gesellschaft, Tyskland) siden 2009 Formand for arbejdsgruppen Non-Antibiotics, PEG siden 2010 Medlem af forskningsråd, Sygehus Sønderjylland, Medical Advisor for Dansk Morbus Bechterew forening siden

18 Medlem i arbejdsgruppe til udvikling af NBV spondyloarthritis, Dansk Reumatologisk Selskab Medlem af Arbejdsgruppe Basalforskning, PEG (Paul Ehrlich Gesellschaft) Louise Thuesen Hermansen Medlem af styregruppe for Tidlig Diagnose af Spondylartropati, siden 2011 Alice Ashouri Christiansen Medlem af Lægeforeningen siden 2010 Medlem af Yngre Læger siden 2010 Medlem af Yngre Reumatologer siden 2012 Medlem af Dansk Reumatologisk Selskab siden 2012 Medlem af Gigtforeningen siden 2013 Medlem af Ph.d.-klubben i Sygehus Sønderjylland, siden 2014 Medlem af American College of Rheumatology siden 2015 Ulrich Weber Internationalt medlem af American College of Rheumatology siden Medlem af Assessments in SpondyloArthritis (ASAS) International Society ( siden Medlem af OMERACT (Outcome Measures in Rheumatology) MRI ved hofte osteoartrit speciel interessegruppe siden Medlem af EULAR arbejdsgruppe til udvikling af EULAR anbefalinger for brug af billeddiagnostik ved spondyloarthritis i klinisk praksis siden Medlem af ASAS MRI ved spondyloarthritis arbejdsgruppe siden Medlem af Danish Imaging Summit Board Helle Feddersen Medlem af Dansk Sygeplejeråd siden 1986 Medlem af Gigtforeningen siden 2013 Medlem af Dansk Selskab for Sygeplejeforskning siden 2013 Medlem af metodeklub, kvalitative forskere ved SDU, sundhedsvidenskab siden 2013 Medlem af Ph.d.-klubben i Sygehus Sønderjylland siden 2014 Dorota Küttel Medlem af Lægeforeningen siden 2006 Medlem af Yngre Læger siden 2006 Medlem af Yngre Reumatologer siden 2008 Medlem af Dansk Reumatologisk Selskab siden 2013 Medlem af Gigtforeningen siden 2014 Medlem af Ph.d.-klubben i Sygehus Sønderjylland, siden

19 Medlem af EMEUNET (The Emerging Eular Network) siden 2014 Medlem af ISEMIR International Society for Musculosceletal Imaging in Rheumatology siden 2015 Pia Lysdal Veje Medlem af Dansk Sygeplejeråd siden 1992 Medlem af Ph.d. klubben SHS siden 2014 Medlem af Metodeklubben ved SDU siden Optræden i massemedier Presseklip Navnlig Navne Berlingske. Kort om modtaget støtte fra Gigtforeningen på kr. Jette Primdahl 14. marts 2016 "Patienter kan også forske" Ugeskrift for læger. Kim Hørslev-Petersen 8. august 2016 Rheumatology Advisor Reproducibility of SIJ Classification in Axial SpA, reference til Christiansen AA, Hendricks O, Kuettel D, Limited Reliability of Radiographic Assessment of Sacroiliac Joints in Patients with Suspected Early Spondyloarthritis. November Brug for forskning i effekten af medicinsk cannabis Ledsager, Gigtforeningen. Oliver Hendricks 16. december Løbende redaktionsarbejde Annals of the Rheumatic Diseases Weber, U Arthritis & Rheumatology Weber, U Arthritis Care & Research Weber, U Arthritis Care & Research Christiansen, A. A

20 European Radiology Weber, U International Journal of Rheumatology Weber, U Journal of Rheumatology Weber, U Microbial Drug Resistance Hendricks, O. april 2016 Rheumatology Primdahl, J. juli 2016 Rheumatology International Primdahl, J. juni 2016 RMD Open, Rheumatic & Musculosceletal Diseases Weber, U Formand for bedømmelsesudvalg Syddansk Universitet (Ekstern organisation) Primdahl, J. (Formand) feb. 2016, lektor 11 Medlem af bedømmelsesudvalg The Swedish Research Council (Ekstern organisation) Hørslev-Petersen, K. (Medlem) apr Aarhus Universitet (Ekstern organisation) Primdahl, J. (Medlem) 6. jan. 2016, ph.d. forsvar Journal of Microbiology, Biotechnology and Food Sciences (Ekstern organisation) Hendricks, O. (Medlem) jan Microbial Drug Resistance (Ekstern organisation) Hendricks, O. (Medlem) jan